A sudden loss of vision, known as non-arteritic anterior ischemic optic neuropathy (NAION), is considered a serious side effect of medications like Fildena Chewable 100 mg containing sildenafil citrate. While rare, it is important to understand why this side effect is considered serious:

1. Irreversible Vision Loss: NAION is a condition characterized by sudden, painless vision loss in one or both eyes. It occurs when there is a sudden decrease or loss of blood flow to the optic nerve, resulting in damage to the nerve cells responsible for vision. In some cases, NAION can lead to irreversible vision loss or permanent blindness in the affected eye(s).
   
2. Potential Association with PDE5 Inhibitors: PDE5 inhibitors, including sildenafil citrate (the active ingredient in Fildena Chewable 100mg), have been associated with a small but increased risk of NAION. While the exact mechanism by which PDE5 inhibitors may contribute to NAION is not fully understood, it is thought to involve changes in blood flow and vascular function within the optic nerve and surrounding structures.
   
3. Warning from Regulatory Agencies: Regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have issued warnings about the potential risk of NAION associated with the use of PDE5 inhibitors, including sildenafil citrate. These warnings highlight the importance of informing healthcare providers and patients about the potential risk of vision loss and the need for prompt medical attention if symptoms occur.
   
4. Precautionary Measures: While the risk of NAION is low, it is important for individuals taking medications like Fildena Chewable 100 mg to be aware of the potential symptoms of vision loss, including sudden changes in vision, blurred vision, or loss of vision in one or both eyes. If these symptoms occur, individuals should seek immediate medical attention to assess and manage the condition.
   
5. Individual Risk Factors: Certain risk factors may increase the likelihood of experiencing NAION while taking PDE5 inhibitors, including older age, pre-existing eye conditions (such as optic nerve disorders or retinal vascular disease), diabetes, hypertension, hyperlipidemia, smoking, and a history of NAION in one eye.
   

Overall, while NAION is considered a serious side effect of medications like Fildena Chewable 100 mg, it is rare, and the benefits of treatment for erectile dysfunction should be weighed against the potential risks. Individuals taking Fildena Chewable 100 mg should be informed about the potential risk of vision loss and advised to seek medical attention if they experience any changes in vision while taking the medication.



 
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