Flibanserin, marketed under the brand name Fliban, is a medication primarily used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. This condition is characterized by a persistent lack of sexual desire that causes distress or interpersonal difficulty. While Fliban 100 mg can be effective in treating HSDD, there are certain medical conditions for which its use may be contraindicated or require caution. Contraindications are medical conditions or situations in which a medication should not be used due to the risk of harm or adverse effects. Here are some medical conditions that may be contraindicative to the use of Fliban 100 mg:
Hepatic Impairment: Flibanserin is metabolized in the liver, and hepatic impairment can affect its metabolism and increase the risk of adverse effects. Therefore, individuals with severe liver disease or impairment may be contraindicated from using Fliban 100 mg.
Alcohol Use: Fliban 100 mg has a significant interaction with alcohol, leading to severe hypotension (low blood pressure) and syncope (fainting). Therefore, individuals with a history of alcoholism or current alcohol use disorder may be contraindicated from using Fliban.
Use with CYP3A4 Inhibitors: Fliban is primarily metabolized by the CYP3A4 enzyme in the liver. Concomitant use of strong CYP3A4 inhibitors may increase Fliban levels in the body, leading to an increased risk of adverse effects. Therefore, the use of Fliban 100 mg with strong CYP3A4 inhibitors may be contraindicated or require dose adjustment.
Hypersensitivity: Individuals who have demonstrated hypersensitivity or allergic reactions to Fliban or its components should not use Fliban 100 mg.
It's essential to discuss your medical history and any existing medical conditions with your healthcare provider before starting Fliban 100 mg. Your healthcare provider can assess your individual risk factors and determine whether Fliban is appropriate for you. Additionally, they can provide guidance on proper usage, potential side effects, and any necessary precautions to take while using the medication. Never start or stop any medication without consulting your healthcare provider.